The Canishield® 1.04g collar for large dogs offers long-lasting triple protection against parasites.• Kills and repels the mosquito that transmits leishmaniasis (Phlebotomus perniciosus) for 5 and a half months. • Kills ticks (Ixodes ricinus) for 6 months. • Kills fleas (Ctenocephalides felis) for 16 weeks. It is suitable for dogs from 7 weeks of age. The collar is odorless and waterproof and is safe and easy to put on thanks to the adjustable strap. Deltamethrin, the active ingredient in the collar, is constantly released by rubbing the collar on the dog's neck. This forms a uniform protective barrier over the entire body of the animal through the lipid layer of the skin. The active ingredient never enters the dog's bloodstream. When fleas, ticks or sand flies come into contact with Deltamethrin, they are quickly paralyzed and die. Although parasites proliferate in the environment as temperatures rise, the animal must be protected all year round. For optimal protection, it is recommended to apply Beaphar Canishield® before the peak of the parasite infestation season. Instructions Do not remove the collar from the protective cover until just before application.